Thursday, May 8, 2014

How XP is inherited?

As we already discussed several times in my previous pots for the other disorder that every cell has 2 copies of each gene: one inherited from the mother and one from father.


Xeroderma Pigmentosum (XP) follows as ‘autosomal recessive’ inheritance pattern in which a mutation must be present in both copies of the gene in order to show its symptoms in the affected individual ¾ which indicates that both parents must pass on a genetic mutation for a child to be affected. A person who has only one copy of the gene mutation is called a carrier. When both the parents are carriers of recessive mutation in the same gene, there is a 25% chance for a child to inherit 2 mutations to be affected.


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