What is Epidermolysis Bullosa (EB)?

Epidermolysis Bullosa (EB) is a group of blistering skin condition. The shin is so fragile in people with Epidermolysis Bullosa (EB) that even minor rubbing may cause blistering—the person with Epidermolysis Bullosa may not be aware of rubbing or injuring the skin even though blisters develop. In severe EB, blisters are not confined to the outer layer of the skin. They may develop inside the body in such places as the linings of the mouth, esophagus, stomach, intestines, upper airway, bladder and genital.

Epidermolysis Bullosa (EB) encompasses over 30 phenotypically or genotypically distinct entities which share as a common feature mechanical fragility of epithelial lined or surfaced tissues, most notably the ‘skin’. A characteristic feature of all types of EB is the presence of recurrent blistering or erosion, the result of even minor traction to these tissues.

Sufferers of Epidermolysis Bullosa (EB) have compared to sores to 3^rd degree burns.