Friday, July 20, 2012



For patents with this autosomal recessive disorder ‘Congenital Insensitivity to Pain (CIP)’ ‘Cognition’ and ‘Sensation’ are otherwise normal for example the patient can still feel discriminative touch (though not always temperature) and there is no detectable physical abnormalities.

Children with this condition often suffer oral cavity damage both in and around the oral cavity (such as having bitten of the tip of their tongue) or fractures to bones. Unnoticed infection and ‘corneal damage’ due to foreign objects in the eye are also found. Because the child can not feel pain they may not respond to problems, thus being at a higher risk of more severe disease or otherwise.

In some patients a mild intellectual disability as well as an impaired corneal reflect also noticed. 

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