Wednesday, July 18, 2012


What is Congenital Insensitivity to Pain (CIP)?

Congenital Insensitivity to Pain (CIP) also called Hereditary Sensory Automatic Neuropathy (HSAN) is a disease that affects the centry nerves that is caused by a genetic mutation that prevents the formation of nerve cells called nociceptors or axonicas endings also called pain nerves, that are specialized pain receptors to feel pressure, temperatures and stretching in and around their tissues. 

There is a similar kind of disease called Congenital Insensitivity to pain with Anhidrosis (CIPA) in which the nervous system prevents the sensation of pain, heat, cold or any real sensation with inability to sweat normally.

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