Monday, May 13, 2013

History ... (2/3)

During the late 19th century, some patients with EDS displayed their hyperextensibility as performers at travelling shows with titles such as ‘elastic lady’ or ‘The India Rubber Man’.

In 1901, Danish Dermatologist Dr. Edvard Lauritz Ehlers (1863–1937) gave further recognition to the syndrome, when he published details of a patient with lax joints, hyperextensible skin and a tendency to bruising. The patient gave a history of delayed walking and frequent subluxations of the knees. This case was demonstrated at the Dermatological Society of Denmark in 1899.

A further case of EDS was identified by French Physician Dr. Henri-Alexandre Danlos (1844–1912) in 1908. Danlos re-examined a patient who had previously been examined by Hallopeau and de Lepinay with a diagnosis of ‘juvenile pseudodiabetic xanthoma’. The patient presented with lesions on the elbows and knees. However, Danlos disagreed with this diagnosis and Pautier (1908), a pathologist, assisted Danlos with further investigations. He suggested the skin lesions were vascular and inflammatory due to trauma. 

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