Symptoms ....

Tetra Amelia Syndrome [TAS] is characterized by the complete absence of all 4 limbs and following anomalies may involve:

Cranium & Face

¶      Cleft Lip/Cleft Palate

¶      Micrognathia

¶      Microtia

¶      Single Naris

¶      Choanal Atresia

¶      Absence Of Nose

Eyes

¶      Microphthalmia

¶      Microcornea

¶      Cataract

¶      Coloboma

¶      Palpebral Fusion

Urogenital System

¶      Renal Agenesis

¶      Persistence Of Cloaca

¶      Absence Of External Genitalia

¶      Atresia Of Vagina

Anus: Atresia

Heart

Lungs: Hypoplasia/aplasia

Skeleton

¶      Hypoplasia/absence of pelvic bones

¶      Absence of ribs, absence of vertebrae

 Central nervous system

¶      Agenesis Of Olfactory Nerves,

¶      Agenesis Of Optic Nerves

¶      Agenesis Of Corpus Callosum

¶      Hydrocephalus

As we discussed earlier the affected infants are often stillborn or die shortly after birth.