Scientists from China and the USA have identified a genetic region
linked to 'werewolf syndrome'.
Researchers from the University of Southern
California, USA, working with scientists Prof. Dr. Xue Zhang of medical
genetics at the Peking Union Medical College from Beijing, China,
studied the genome of a Chinese man with ‘Hypertrichosis’
and identified a defective region of the X chromosome they
believe is linked to the condition. As per the
discovery the man had an extra stretch of DNA known as an
'inserted-sequence' in a region very close to SOX3, a gene known
to be involved in hair growth. The inserted sequence had altered the activity
of SOX3, leading to excessive hair growth.
The finding was also confirmed in a Mexican family,
in which several members had ‘Hypertrichosis’. But in this case, although
the location of the insertion was the same, the 'inserted sequence' itself was
not the same as in the Chinese man. This suggests it is the region of the X
chromosome that is more important in controlling hair growth, rather
than the exact defect itself.
This study may lead to improvements
in the treatment of Hypertrichosis, but the researchers also hope the discovery
could lead to treatments for male pattern baldness. Prof. Pragna Patel, who
is also the part of the stufy, from the University of Southern California told
the Daily Mail: 'If in fact the inserted sequences turn on a gene that can
trigger hair growth, it may hold promise for treating baldness'.
The
study was published in the American Journal of Human Genetics.
Source: www.huffingtonpost.com/2011/06/07/wolf-boy-larry-gomez-wolf-boy-werewolf-syndrome_n_872229.html
No comments:
Post a Comment